Republicans mindlessly oppose Iran nuclear deal  —  Republicans are opposed to President Obama's deal with the Iranians — whatever it is.  —  A couple of minutes after 9 p.m. on Saturday, word crossed the news wires that negotiators in Geneva had reached an agreement on Iran's nuclear program.

Steubenville case: Four more charged, including superintendent, volunteer coach  —  An Ohio grand jury investigating an alleged cover-up in the Steubenville rape case has indicted four more people, including the school superintendent and an assistant football coach.

Obamacare deadline tests Dem patience  —  Some Capitol Hill Democrats are preparing to launch broadsides against President Barack Obama if the Affordable Care Act website isn't fixed by the end of the month.  —  That will come in the form of more aggressive scrutiny in Republican-led oversight hearings …

No, the Failure of Obamacare Would Not Lead to Single-Payer  —  More than a few conservatives are of the opinion that should the Affordable Care Act fail to achieve its goals, it would make the adoption of single-payer health insurance in the United States more likely.

Right-wing extremists face new moral conundrum  —  When Healthcare.gov actually starts working, GOP will have to choose between politics or their constituents' health  —  The confluence of two pieces of news last week will place Republicans at a moral crossroads — either by this weekend …

Remarks by the President on Immigration Reform — San Francisco, CA  —  THE PRESIDENT: Hello, everybody!  (Applause.)  Well, hello, San Francisco!  (Applause.)  It is great to be back in California.  It is great to be with all of you.  I love San Francisco.  (Applause.)  You got great food.

Chilling new details in Sandy Hook shooting  —  With no co-conspirators identified, Sedensky said no criminal charges will be filed.  AP Photo  —  Close  —  The 48-page report lays out the horror of Sandy Hook Elementary School in methodical detail.  It's all there: The sound of crashing glass …

Creigh Deeds: ‘I am alive for a reason’  —  Virginia State Sen. Creigh Deeds says he's “alive for a reason” in his first comments to the media following an altercation at his residence last week where he suffered multiple stab wounds to the head and torso and his son killed himself with a rifle.

The dirty secrets behind Boehner's ‘spiking’ Obamacare premiums  —  Speaker John Boehner, grappling with Obamacare.  (House of Representatives)  —  Perhaps in an effort to defuse reports that House Speaker John Boehner is making out pretty well as a first-time insurance customer under …

Welcome aboard, Katie.  Anchors aweigh!  —  Today, I am incredibly excited to announce that Katie Couric is joining Yahoo as our Global Anchor.  Starting in early 2014, Katie will lead a growing team of correspondents at Yahoo News who will cover the world's most interesting stories and newsmakers.

What If There Simply Aren't More Antibiotics to be Discovered?  —  Antibiotic resistance, like climate change, is one of those issues that has been blinking red on the world's dashboard for decades.  Everyone agrees it's potentially disastrous—in fact, has already reached crisis stage in some areas …

New Tax Return Shows Karl Rove's Group Spent Even More On Politics Than It Said  —  On its 2012 tax return, GOP strategist Karl Rove's dark money behemoth Crossroads GPS justified its status as a tax-exempt social welfare group in part by citing its grants of $35 million to other similarly aligned nonprofits.

GOP Rep. Kingston: Not ‘responsible’ to let ObamaCare fail  —  A Republican lawmaker running for Senate in Georgia is calling for improvements to ObamaCare, breaking with his party's proclaimed policy to simply let the law self-destruct.  —  Rep. Jack Kingston (R-Ga.) on Monday questioned whether …

Before we stuff ourselves with stuffing and trim the tree this Thanksgiving, TIME asks some public figures—from Michelle Obama to Rick Warren to our astronauts orbiting Earth—to share what they're grateful for.  —  My dad used to have an expression.  He said, “It's a lucky person who gets …

New Warning: Morning-After Pill Doesn't Work for Women Over 176 Pounds  —  The European manufacturer of a pill identical to Plan B says its product won't work for women who weigh more than 176 pounds.  Will American pharma companies warn women of weight limits?  —  Maybe not as effective as you think.