Live Updates: Mississippi Abortion Law Arguments Conclude at Supreme Court  —  The arguments are over.  Here's what happens next.  —  The justices will cast tentative votes at a private conference in the coming days.  The senior justice in the majority will then assign the majority opinion to a colleague or, just as likely, keep it.

Trump tested positive for Covid few days before Biden debate, chief of staff says in new book  —  Mark Meadows makes stunning admission in new memoir obtained by Guardian, saying a second test returned negative  —  Donald Trump tested positive for Covid-19 three days before his first debate …

BREAKING: Stacey Abrams is running for Georgia governor in 2022  —  Stacey Abrams launched a campaign for Georgia governor on Wednesday with a pledge to fight for economic equality and expand healthcare access, setting up a potential rematch against Republican Gov. Brian Kemp in one of the nation's …

IOC member says Chinese tennis player Peng Shuai is ‘fine’ after video call  —  A long-standing member of the International Olympic Committee said people who spoke to missing Chinese tennis player Peng Shuai have reached the “unanimous conclusion” that she is “fine.”

Ghislaine Maxwell trial: Sex crimes accuser testifies Jeffrey Epstein took her to meet Trump when she was 14  — A woman who says she was sexually abused by Jeffrey Epstein and Ghislaine Maxwell testified that Epstein took her to meet Donald Trump at his Florida club when she was 14 years old.

Exclusive: Trump's social media venture seeks $1 billion raise, sources say … Former President Donald Trump's new social media venture is seeking to raise up to $1 billion by selling shares to hedge funds and family offices at several times the valuation it commanded in a deal …

Chilling Videos, Journal Found as Parents Face Scrutiny in Michigan School Shooting  —  Ethan Crumbley, 15, had displayed “behavior in the classroom” that school officials “felt was concerning.”  —  OXFORD, Michigan—The shooter who allegedly killed four students and injured seven …

First confirmed US case of Omicron coronavirus variant detected in California  —  Tonight, CNN's Anderson Cooper and Chief Medical Correspondent Dr. Sanjay Gupta host a global town hall on the Omicron coronavirus variant and Dr. Anthony Fauci will answer viewer questions.  Watch live at 9 p.m. ET on CNN.

Marcus Lamb, head of Daystar, a large Christian network that discouraged vaccines, dies after getting covid-19  —  Marcus Lamb, founder of the large Christian network Daystar, died Tuesday after contracting the coronavirus.  Lamb's network during the pandemic has made the virus a huge focus …

Planned Parenthood Los Angeles says hack breached about 400,000 patients' information  —  A hacker gained access to the personal information of hundreds of thousands of Planned Parenthood patients last month, the reproductive health-care group's Los Angeles branch said Wednesday.

Katie Curran O'Malley, retired judge and former first lady, launches bid for Maryland attorney general  —  Katie Curran O'Malley is running for Maryland attorney general, setting the stage for an unprecedented battle between the former first lady and her husband's lieutenant governor.

Marty Walsh is weighing a run for Massachusetts governor  —  BOSTON — Labor Secretary Marty Walsh is weighing whether to return home to Massachusetts and run for governor next year, according to two sources with knowledge of his deliberations.  —  A number of Democrats have called Walsh …

Governor Charlie Baker telling allies he isn't running for reelection  —  Massachusetts Governor Charlie Baker, the Republican who maintained the enduring support of his blue state constituents through boom times, the Trump presidency, and in the face of mass death during the COVID-19 pandemic …

Hedge fund CEO readies Senate bid despite Oz announcement  —  PHILADELPHIA — Hedge fund CEO David McCormick is preparing a run for Senate in Pennsylvania, a move that would upend the Republican primary for the third time in as many weeks.  —  McCormick, who runs Bridgewater Associates …

Why the Discredited Dossier Does Not Undercut the Russia Investigation  —  Donald J. Trump and his backers say revelations about the Steele dossier show the Russia investigation was a “hoax.”  That is not what the facts indicate.  —  WASHINGTON — Former President Donald J. Trump and his allies …

“This Is Blackface”: Inside The Virtual Reality Company Trying To Scale Diversity Training  —  Mursion tells big corporate clients that its VR simulations will help teach racial sensitivity.  But the actors playing its Black characters are often white.  —  Copy

POLITICO Playbook: Scoop: Conservatives plot government shutdown over vaccine mandate  —  DRIVING THE DAY  —  FRIDAY'S SHUTDOWN SHOWDOWN GETS REAL — Conservatives on both sides of the Capitol are privately plotting to force a government shutdown Friday in an effort to defund …

America is Running on Fumes  —  Sign up for Derek's newsletter here.  —  Let's start with a simple mystery: What happened to original blockbuster movies?  —  Throughout the 20th century, Hollywood produced a healthy number of entirely new stories.  The top movies of 1998—including Titanic …

Covid-19 Vaccine Effectiveness in New York State  —  Abstract  —  Population-based data from the United States on the effectiveness of the three coronavirus disease 2019 (Covid-19) vaccines currently authorized by the Food and Drug Administration are limited.